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Dr. Feils Alzheimer Strategie


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Übersicht

Wochenplan

Wochenplan

Dr. Wolfgang Feil

Dr. Wolfgang Feil, geboren 1959, ist Ehemann sowie Vater zweier Kinder. Er ist aktiver Ausdauersportler (Marathon-Bestzeit unter 3 Stunden). An der Universität Tübingen studierte er die Fächer Biologie und Sportwissenschaft und ergänzte dann sein Studium mit Innovationsmanagement in Berlin. Beruflich leitet Dr. Wolfgang Feil die Forschungsgruppe Dr. Feil, die sich besonders in den Gebieten Arthrose, Allergie/ Neurodermitis sowie Stoffwechselaktivierung / Vitalität verdient gemacht hat. Zusätzlich berät er als Nährstoffmedizinischer-Berater mehrerer Spitzensportler, Bundesligavereine sowie Nationalmannschaften. [... mehr Informationen zu Dr. Feil]

Literaturempfehlung

Lauf-Diät Buch

Lauf-Diät

Wie Sie aus der Alzheimer-Strategie wissen, sollte die Ernährung bei einer Alzheimer-Erkrankung besonders reich an Gewürzen und Omega-3 Fettsäuren in Form von Fisch und Speiseleinöl sein. Ebenso sollte eine Alzheimer-Strategie Bewegungseinheiten beinhalten. Im Buch „Die Lauf-Diät“ finden Sie einerseits viele Rezepte mit Gewürzen und Omega-3 Fettsäuren sowie andererseits auch Bewegungspläne, um Alzheimer-Beschwerden vorzubeugen oder zu lindern.

von Dr. Wolfgang Feil und Herbert Steffny

Lauf-Diät Buch

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Studien

  • Aggarwal, B. B., & Shishodia, S. (2004). Suppression of the Nuclear Factor-κB Activation Pathway by Spice-Derived Phytochemicals: Reasoning for Seasoning. Annals of the New York Academy of Sciences, 1030(1), 434-441.
  • Arntzen, K. A., Schirmer, H., Wilsgaard, T., & Mathiesen, E. B. (2010). Moderate wine consumption is associated with better cognitive test results: a 7 year follow up of 5033 subjects in the Tromsø Study. Acta Neurologica Scandinavica, 122, 23-29.
  • Bieschke, J., Russ, J., Friedrich, R. P., Ehrnhoefer, D. E., Wobst, H., Neugebauer, K., et al. (2010). EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity. Proceedings of the National Academy of Sciences, 107(17), 7710-7715.
  • Cho JY, U. H., Kang EB, Cho IH, Kim CH, Cho JS, Hwang DY. (2010). The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer’s disease in NSE/APPsw-transgenic mice. International Journal of Molecular Medicine, 25(3), 337-346.
  • Cole, G. M., Lim, G. P., Yang, F., Teter, B., Begum, A., Ma, Q., et al. (2005). Prevention of Alzheimer’s disease: Omega-3 fatty acid and phenolic anti-oxidant interventions. [doi: DOI: 10.1016/j.neurobiolaging.2005.09.005]. Neurobiology of Aging, 26(1, Supplement 1), 133-136.
  • Cole, G. M., Ma, Q.-L., & Frautschy, S. A. (2009). Omega-3 fatty acids and dementia. [doi: DOI: 10.1016/j.plefa.2009.05.015]. Prostaglandins, Leukotrienes and Essential Fatty Acids, 81(2-3), 213-221.
  • Darvesh, A. S., Carroll, R. T., Bishayee, A., Geldenhuys, W. J., & Van der Schyf, C. J. (2010). Oxidative stress and Alzheimer’s disease: dietary polyphenols as potential therapeutic agents. Expert Review of Neurotherapeutics, 10(5), 729-745.
  • Eckert, A., Keil, U., Kressmann, S., Schindowski, K., Leutner, S., Leutz, S., et al. (2003). Effects of EGb 761® Ginkgo biloba Extract on Mitochondrial Function and Oxidative Stress. Pharmacopsychiatry, 36(S 1), 15,23.
  • Eskelinen, M. H., & Kivipelto, M. (2010). Caffeine as a Protective Factor in Dementia and Alzheimer’s Disease. [10.3233/JAD-2010-1404]. Journal of Alzheimer’s Disease, 20(0), 167-174.
  • Freund-Levi, Y., Eriksdotter-Jonhagen, M., Cederholm, T., Basun, H., Faxen-Irving, G., Garlind, A., et al. (2006). {omega}-3 Fatty Acid Treatment in 174 Patients With Mild to Moderate Alzheimer Disease: OmegAD Study: A Randomized Double-blind Trial. Arch Neurol, 63(10), 1402-1408.
  • Frydman-Marom, A., Levin, A., Farfara, D., Benromano, T., Scherzer-Attali, R., Peled, S., et al. (2011). Orally Administrated Cinnamon Extract Reduces β-Amyloid Oligomerization and Corrects Cognitive Impairment in Alzheimer›s Disease Animal Models. PLoS ONE, 6(1), e16564.
  • Grzanna, R., Phan, P., Polotsky, A., Lindmark, L., & Frondoza, C. G. (2004). Ginger Extract Inhibits β-Amyloid Peptide–Induced Cytokine and Chemokine Expression in Cultured THP-1 Monocytes. The Journal of Alternative and Complementary Medicine, 10(6), 1009-1013.
  • He, G., Luo, W., Li, P., Remmers, C., Netzer, W. J., Hendrick, J., et al. (2010). Gamma-secretase activating protein is a therapeutic target for Alzheimer/’s disease. [10.1038/nature09325]. Nature, 467(7311), 95-98.
  • Helen, K., Hongli, X., Lin, L., & John, G. (2000). Attenuation of neurodegeneration-relevant modifications of brain proteins by dietary soy. BioFactors, 12(1), 243-250.
  • Hooshmand, B., Solomon, A., Kåreholt, I., Leiviskä, J., Rusanen, M., Ahtiluoto, S., et al. (2010). Homocysteine and holotranscobalamin and the risk of Alzheimer disease. Neurology, 75(16), 1408-1414.
  • Hsieh, H.-M., Wu, W.-M., & Hu, M.-L. (2009). Soy isoflavones attenuate oxidative stress and improve parameters related to aging and Alzheimer‘s disease in C57BL/6J mice treated with d-galactose. [doi: DOI: 10.1016/j.fct.2008.12.026]. Food and Chemical Toxicology, 47(3), 625-632.
  • Joseph, J. A., Shukitt-Hale, B., & Willis, L. M. (2009). Grape Juice, Berries, and Walnuts Affect Brain Aging and Behavior. J. Nutr., 139(9), 1813S-1817.
  • Kato-Kataoka, A., Sakai, M., Ebina, R., Nonaka, C., Asano, T., & Miyamori, T. (2010). Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints. Journal of clinical biochemistry and nutrition, 47(3), 246-255.
  • Kim, J., Lee, H. J., & Lee, K. W. (2010). Naturally occurring phytochemicals for the prevention of Alzheimer’s disease. Journal of Neurochemistry, 112(6), 1415-1430.
  • Li, J., Wang, Y. J., Zhang, M., Xu, Z. Q., Gao, C. Y., Fang, C. Q., et al. (2011). Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease. Neurology.
  • Lund, D., Ruggiero, A. M., Ferguson, S. M., Wright, J., English, B. A., Reisz, P. A., et al. (2010). Motor neuron-specific overexpression of the presynaptic choline transporter: impact on motor endurance and evoked muscle activity. [doi: DOI: 10.1016/j.neuroscience.2010.09.057]. Neuroscience, 171(4), 1041-1053.
  • Luo, Y., Smith, J. V., Paramasivam, V., Burdick, A., Curry, K. J., Buford, J. P., et al. (2002). Inhibition of amyloid-β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proceedings of the National Academy of Sciences of the United States of America, 99(19), 12197-12202.
  • Maczurek, A., Hager, K., Kenklies, M., Sharman, M., Martins, R., Engel, J., et al. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer‘s disease. [doi: 10.1016/j.addr.2008.04.015]. Advanced Drug Delivery Reviews, 60(13-14), 1463-1470.
  • Mishra, S., & Palanivelu, K. (2008). The effect of curcumin (turmeric) on <i>Alzheimer’s disease</i>: An overview (Vol. 11).
  • O’Sullivan-Coyne, G., O’Sullivan, G. C., O’Donovan, T. R., Piwocka, K., & McKenna, S. L. (2009). Curcumin induces apoptosis-independent death in oesophageal cancer cells. Br J Cancer, 101(9), 1585-1595.
  • Oster, T., & Pillot, T. (2010). Docosahexaenoic acid and synaptic protection in Alzheimer’s disease mice. [doi: DOI: 10.1016/j.bbalip.2010.02.011]. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1801(8), 791-798.
  • Parachikova, A., Green, K. N., Hendrix, C., & LaFerla, F. M. (2010). Formulation of a Medical Food Cocktail for Alzheimer’s Disease: Beneficial Effects on Cognition and Neuropathology in a Mouse Model of the Disease. PLoS ONE, 5(11), e14015.
  • Philip, S., Patrick, J. G. H. K., Frans, R. J. V., Marcel, G. M. O. R., Richard, J. W., David, W., et al. (2010). Efficacy of a medical food in mild Alzheimer’s disease: A randomized, controlled trial. 6(1), 1-10.e11.
  • Reynolds, E. H. (2002). Folic acid, ageing, depression, and dementia. BMJ, 324(7352), 1512-1515.
  • Rolland, Y., Pillard, F., Klapouszczak, A., Reynish, E., Thomas, D., Andrieu, S., et al. (2007). Exercise Program for Nursing Home Residents with Alzheimer’s Disease: A 1-Year Randomized, Controlled Trial. Journal of the American Geriatrics Society, 55(2), 158-165.
  • Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., et al. (1997). A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer’s Disease. New England Journal of Medicine, 336(17), 1216-1222.
  • Shenk, J. C., Liu, J., Fischbach, K., Xu, K., Puchowicz, M., Obrenovich, M. E., et al. (2009). The effect of acetyl-L-carnitine and R-[alpha]-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer’s disease. [doi: 10.1016/j.jns.2009.03.002]. Journal of the Neurological Sciences, 283(1-2), 199-206.
  • Smith, A. D., Smith, S. M., de Jager, C. A., Whitbread, P., Johnston, C., Agacinski, G., et al. (2010). Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. PLoS ONE, 5(9), e12244.
  • Vingtdeux, V., Giliberto, L., Zhao, H., Chandakkar, P., Wu, Q., Simon, J. E., et al. (2010). AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism. Journal of Biological Chemistry, 285(12), 9100-9113.
  • Xu, W. L., Atti, A. R., Gatz, M., Pedersen, N. L., Johansson, B., & Fratiglioni, L. (2011). Midlife overweight and obesity increase late-life dementia risk. Neurology, 76(18), 1568-1574.
  • Yang, F., Lim, G. P., Begum, A. N., Ubeda, O. J., Simmons, M. R., Ambegaokar, S. S., et al. (2005). Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo. Journal of Biological Chemistry, 280(7), 5892-5901.


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